Dra. Dewajani Purnomosari, M.Si., Ph.D.

Dewajani Purnomosari bergabung di (saat itu) Bagian Histologi sejak tahun 1998 dengan SK Rektor, setelah menyelesaikan studi Magister Bioteknologi di Pusat Antar Universitas (PAU) UGM. Pada tahun 1999, Neni mendapat kesempatan mendapatkan pelatihan di Vrije Universiteit Belanda selama 3 bulan, dan tahun 2001 memulai program doktor dari universitas yang sama. Neni diangkat menjadi PNS pada tahun 2005 dan tahun 2006 menyelesaikan program doktor dari Utrecht Medical Center dalam bidang Developmental Biology and Oncology. Setelah menyelesaikan program doktor, Neni langsung terlibat dalam aktivitas belajar mengajar. Selama bergabung di departemen, pernah menjadi koordinator penelitian, koordinator pendidikan, dan saat ini diberi kepercayaan sebagai bendahara departemen. Selain sebagai pengajar, juga terlibat sebagai fasilitator Good Laboratory Clinical Practice (GCLP), menjadi ketua tim Biosafety FK KMK, menjadi anggota tim System Management Biorisk Laboratory (SMBL) UGM, sejak tahun 2017 ditunjuk sebagai anggota asesor Komisi National Authority for Containment (NAC) dalam rangka eradikasi Polio dan sejak 2016 terlibat aktif sebagai fasilitator di Asosiasi Biorisiko Indonesia (ABI). Selama menjalani program doktor, mendapat kesempatan mengikuti pelatihan di Heidelberg-Jerman, Taiwan dan Hawaii. Mendapat kesempatan menempuh pasca doktoral selama 1 tahun di WHO-IARC di dalam grup Genetic Susceptibility. Minat penelitian utama adalah genetika molekuler kanker payudara, imunologi dan pengaruh bahan alam pada galur sel kanker dan pada hewan coba.

Dewajani Purnomosari (Neni) joined (at that time named) the Department of Histology in 1998 after completing his Masters in Biotechnology at the Pusat Antar Universitas (PAU) UGM. In 1999, Neni had the opportunity to receive training at Vrije Universiteit Netherlands for 3 months, and in 2001 started a doctoral program at the same university. Neni was appointed a civil servant in 2005. In 2006, she completed a developmental biology and oncology doctoral program at Utrecht Medical Center. After completing the doctoral program, Neni was immediately involved in teaching and learning activities. While at the department, she was a research and education coordinator and is currently entrusted with being the department’s treasurer. Besides teaching, she is also involved as a Good Laboratory Clinical Practice (GCLP) facilitator, being the head of the Biosafety FK-KMK team a member of the UGM System Management Biorisk Laboratory (SMBL) team, 2017 she was appointed as an assessor member of the National Authority for Containment (NAC) Commission in the context of polio eradication and since 2016 has been actively involved as a facilitator at the Asosiasi Biorisiko Indonesia (ABI). During his doctoral program, she had the opportunity to attend training in Germany, Taiwan, and Hawaii. She had the chance to take a post-doctoral degree for 1 year at WHO-IARC in the Genetic Susceptibility group. Her main research interests are molecular genetics of breast cancer, immunology, and the effect of natural substances on cancer cell lines and in experimental animals.

Riwayat Pendidikan

  • Doctor of Philosophy (Ph.D) in Oncology and Developmental Biology, Utrecht University, the Netherlands (2006)
  • Master of Science (M.Sc) in Molecular Genetics, Universitas Gadjah Mada, Indonesia (1997)
  • Bachelor of Science (B.Sc.) in Genetics, Universitas Gadjah Mada, Indonesia (1992)

Riwayat Publikasi (5 Tahun Terakhir)

2025

  • Dewajani Purnomosari, Bilqis Zahra Nabila, Sitarina Widyarini, Mustofa. Targeting immune cells in tumor microenvironment in triple negative breast cancer therapy: future perspective to overcome doxorubicin resistance and toxicity.  Medical Oncology (2025) 42:150. https://doi.org/10.1007/s12032-025-02712-6

2024

  • Teresa Nurtanio, Jajah Fachiroh, Neti Nurani, Dewajani Purnomosari. Lower ERVW-1 and higher VEGF, FLT-1 and HIF-1 gene expression in placentae of low birth babies from Indonesia. Placenta, Volume 154, 2 September 2024, Pages 162-167.
  • Suci Widhiati, Nabila Kirtti Pradipta, Dewajani Purnomosari, Retno Danarti, Alifah Anggraini, Retno Palupi, Niken Trisnowati. Lethal Carmi syndrome (junctional epidermolysis bullosa-pyloric atresia) with a novel and recurrent compound integrin beta 4 heterozygous mutation: A case report, JAAD Case Reports 2024;50:75-8.

2023

  • Gatot Soegiarto and Dewajani Purnomosari. Challenges in the Vaccination of the Elderly and Strategies for Improvement. Pathophysiology 2023, 30, 155–173 .
  • Gatot Soegiarto, Dewajani Purnomosari, Laksmi Wulandari, Bagus Aulia Mahdi, Karin Dhia Fahmita, Satrio Tri Hadmoko, Hendra Ikhwan Gautama, Muhammad Edwin Prasetyo, Dewi Prasetyaningtyas, Pujo Prawiro Negoro, Nur Arafah, Cita Rosita Sigit Prakoeswa, Anang Endaryanto, Desak Gede Agung Suprabawati, Damayanti Tinduh, Eka Basuki Rachmad, Erwin Astha Triyono, Joni Wahyuhadi, Catur Budi Keswardiono, Feby Elyana Wardani, Fitriyah Mayorita, Nunuk Kristiani, Ari Baskoro, Deasy Fetarayani, Wita Kartika Nurani, and Delvac Oceandy. Incidence of SARS-CoV-2 infection in hospital workers before and after vaccination programme in East Java, Indonesia–A retrospective cohort study. The Lancet Regional Health – Southeast Asia 2023;10: 100130
  • Karin Dhia Fahmita,Gatot Soegiarto, Laksmi Wulandari, Dewajani Purnomosari. Impact of Hypertension and Cardiovascular Diseases to Immune Response in COVID-19 Vaccination: A Systematic Review. Indonesian Journal of Tropical and Infectious Disease. 11(1). 44–51. Apr. 2023.
  • Novrita Padauleng, Mustofa Mustofa, Tutik Dwi Wahyuningsih, Dewajani Purnomosari. Chalcone-3 Inhibits the Proliferation of Human Breast Cancer MDA-MB-231 Cell Line. Asian Pacific Journal of Cancer Prevention 2023: 24 (2), 683-691

2022

  • Annisa, Elizabet Henny Herningtyas and Dewajani Purnomosari. High Keratin Secretion of T47D Cell under Hypoxic Condition. The Indonesian Biomedical Journal, Vol.14, No.4, December 2022, p.329-441.
  • Suci Widhiati, Shinta Trilaksmi Dewi, Yefta, Retno Danarti, Hardyanto Soebono, Yulia Eka Irmawati, Monika Puspitasari,N iken Trisnowati, Tri Wibawa, Dewajani Purnomosari, Yohanes Widodo Wirohadidjojo. Modified Non-Cultured Cell Spray Induced Epithelization in LAMB3 Mutation Epidermolysis Bullosa. Clinical, Cosmetic and Investigational Dermatology. Volume 2022:15 pages 2197—2202
  • Gatot Soegiarto, Laksmi Wulandari, Dewajani Purnomosari, Karin Dhia Fahmita, Hendra IkhwanGautama, Satrio Tri Hadmoko, Muhammad Edwin Prasetyo, Bagus Aulia Mahdi, Nur Arafah, DewiPrasetyaningtyas, Pujo Prawiro Negoro, Cita Rosita Sigit Prakoeswa, Anang Endaryanto, Desak Gede Agung Suprabawati, Damayanti Tinduh, Eka Basuki Rachmad, Erwin Astha Triyono, Joni Wahyuhadi, Catur Budi Keswardiono, Feby Elyana Wardani, Fitriyah Mayorita, Nunuk Kristiani, Ari Baskoro, Deasy Fetarayani, Wita Kartika Nurani, Delvac Oceandy. Hypertension is associated with antibody response and breakthrough infection in health care workers following vaccination with inactivated SARS-CoV-2. Vaccine. May 2022
  • Sukma Diani Putri, Siti Rahma Yunianda Nanza, Irianiwati Widodo, Dewajani Purnomosari. The Association of Intra-Tumoral and Stromal Vitamin D Receptor (VDR) Expressions with Molecular Subtypes and Clinicopathological Factors in Breast Carcinoma. April 2022. Asian Pacific Journal of Cancer Prevention 23(4):1169-1175
  • Rizwan Ahmad, Muhammad Riaz, Mohammed Aldholmi, MuhammadAsif Qureshi, Shahab Uddin, Ajaz Ahmad Bhat, Pratheeshkumar Poyil,Mukhtiar Baig, Jalal Pourahmad, Trivadi Ganesan, Abdul Quaiyoom Khan, Zainab Siddiqui, Maha El-Demellawy, Maryam Gholamalizadeh, Dewajani Purnomosari, Elsayed I Salim, Seyedeh Zahra Mousavi Jarrahi, Jian-yeZhang, Sammad Mohammad Nejad, Alireza Mosavi Jarrahi. Development of a Critical Appraisal Tool (AIMRDA) for the Peer-Review of Studies Assessing the Anticancer Activity of Natural Products: A Step towards Reproducibility. Asian Pacific Journal of Cancer Prevention 22(12):3735-3740, January 2022

2021

  • Suci Widhiati, Dewajani Purnomosari, Tri Wibawa, Hardyanto Soebono. The role of gut microbiome in inflammatory skin disorders: A systematic review. Dermatology Report, Vol 14(1), December 2021
  • Suci Widhiyati, Retno Danarti, Niken Trisnowati, Dewajani Purnomosari, Tri Wibawa, Hardyato Soebono, Novel mutations of epidermolysis bullosa identified using whole-exome sequencing in Indonesian Javanese patients, Intractable & Rare Diseases Research 10(2), 2021, March
  • Made Ariyana, Diah R Hadiyati, Irwan T Rachman, Dewajani Purnomosari, Bax Expression of Throphoblast Cells did not Differ between Early and Late Onset Preeclampsia, Indonesian Journal of Obstetrics and Gynecology, Vol 9. No 3. July 2021: 126-129
  • Herman Sumawan, Irwan Taufiqqurachman, Diah Rumekti Hadiati, Dewajani Purnomosari. Expression Trophoblast Cell B-Cell Lymphoma (Bcl2) In Early And Late-Onset Preeclampsia. Mandala of Health Vol. 13, No. 2, Februari 2021, Hal. 52-58

2020

  • Dian Eurike Septyaningtrias, Jajah Fachiroh, Dewi Kartikawati Paramita, Dewajani Purnomosari, Rina Susilowati, Review of immune responses correlated with COVID-19 outcomes: the fight, debacle and aftermath in the Indonesian context, J Med Sci, Volume 52, Number 3 (SI), 2020, Juli: 138-162.